This method allows tissues to be stored below freezing without sustaining damage, potentially extending the shelf life of engineered tissues for future biomedical applications, including drug testing, disease modelling, and therapeutic implants.   Supported by the National Science Foundation (NSF), NASA, and the International Space Station National Laboratory (ISSNL), the Chang Laboratory’s spaceflight experiment is slated for launch in February 2025. This pioneering work not only advances tissue engineering but also lays the groundwork for future innovations in space-based medical manufacturing.