TPO roofing typically comes in thicknesses ranging from 45 to 80 mils, with 60 mil being a common choice for commercial buildings. The right thickness depends on factors such as building use, roof traffic, weather conditions, and expected service life. Thicker TPO membranes can provide added durability and better protection against punctures and wear. When choosing a TPO roofing system, it’s important to consider the building’s specific needs and installation requirements. A professional roofing contractor can help determine the most suitable membrane thickness for your commercial property.